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They are released throughout the day, increasing at mealtimes, and have several functions: Stimulate the production and secretion of insulin in response to eating (glucose-dependent insulin secretion) GLP-1 enhances the sensitivity of alpha cells to glucose, resulting in more glucose-appropriate glucagon secretion Slow digestion and decrease appetite Thus, DPP-4 inhibitors indirectly enhance insulin release, suppress glucagon secretion, and improve glycaemic control
Always make sure to speak to your doctor about your specific health conditions and concerns
Both of these weight average molecular weight ranges are encompassed in the polydispersity molecular weight profile of PGN (Figure 3)
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